Shizune (シズネ, Shizune) is a jōnin-level kunoichi of Konohagakure, a talented medical-nin, as well as the Fifth Hokage's assistant. Shizune is the niece of Dan Katō, a renowned shinobi of Konoha. Some time after her uncle's death, Tsunade, his love interest, left Konoha and Shizune went with her as her attendant and apprentice. The bond between Tsunade and Shizune is strong and, above all, Shizune sees her purpose in life as caring for Tsunade.

Text from wikia

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